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The inhibition of respiratory chain complexes accelerates mitochondrial dysfunction and causes cell apoptosis (142)

A review of the protective effects of natural compounds against chemical-induced hepatotoxicity

NR2B = N-methyl-d-aspartate receptor subtype-2B
Interestingly, we found an increase in fully labelled intracellular glutamate after incubation with [U- 13 C] glutamate in the FTD3 patient-derived astrocytes, suggesting increased glutamate uptake compared to the respective isogenic control

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