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In particular, the chemotherapeutic response and the vulnerability to cisplatin depends on GSTP1, able to induce the conjugation of GSH to electrophilic molecules

However, when ROS levels exceed the redox capacity of the cells, they may cause substantial damage to various macromolecules such as proteins, lipids, and nucleotides, leading to severe cell damage or death [73,74,75]

D dng s dng Hp 35 vin v 72 vin, ng trong l thy tinh vi np nha vn m chc chn, nh gn d mang theo

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The oxidoreductases POR and CYB5R1 catalyze lipid peroxidation to execute ferroptosis

Van Dam NT, van Vugt MK, Vago DR, et al
