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In theory, targeting any node of cysteine-GSH-GPx4 axis seems to be sufficient to induce ferroptosis

It also contributes to good liver function

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[DOI] [PubMed] [Google Scholar] 97.Sasaki Y., Kobara N., Higashino S., Giddings J.C., Yamamoto J

However, at high concentrations, when RNS levels exceed the capability of its detoxification in the biological system, serious damage to cells may occur [147, 148] due to inhibition of mitochondrial respiratory function by competing with O 2 for interaction with cytochrome oxidase [149] and via nitrative/nitrosative stress [150, 151]

Lifestyle habits like getting enough sleep, exercising regularly (combining cardio and weight training), and limiting alcohol intake can help maintain or increase glutathione levels