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When bacteria gets trapped in the pore and becomes infected, the infection is carried on underneath the skin, causing redness and swelling

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So far it is unknown how large the respective contribution of intestinal bacteria and food is to the total requirement of the biotin supply

Consider discussing B12 testing with your vet if your dog has: Had chronic or intermittent diarrhoea for more than a few weeks without a clear resolved cause Lost weight progressively despite adequate food intake Been diagnosed with a chronic gut condition, such as inflammatory bowel disease or exocrine pancreatic insufficiency A history of poor early nutrition, such as a recently rescued stray or previously malnourished dog Been through multiple courses of treatment for digestive symptoms without sustained improvement A young dog or puppy that is not developing or gaining weight as expected Causes of Vitamin B12 Deficiency in Dogs Vitamin B12 deficiency in dogs is almost always caused by a problem with absorption rather than a lack of B12 in the diet

Nat Rev Drug Discov

Hi not sure if this is still relevant to you