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For example, EGCG can dampen the expression of nicotinamide adenine dinucleotide phosphate oxidase (NOX), an enzyme responsible for catalyzing the transfer of electrons to oxygen molecules in the generation of reactive oxygen species (ROS) [83]

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However, this review was limited by the inability to directly compare the pharmacokinetics, pharmacodynamics, and toxicity of oxaliplatin after IV administration with those after HIAC, PIPAC, and HIPEC
Instead of flattening the curve, CJC-1295 elevates the trough levels (the lowest points between pulses) while preserving the natural peaks