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Description
However, further adequately-powered real-world studies with appropriate follow-up periods are needed to confirm the role of adjunctive antioxidants in schizophrenia

It exerts anti-inflammatory effects by inhibiting the gene expression of pro-inflammatory cytokines such as IL-1, IL-1, IL-6, and IL-12p35, downregulating the activity of inflammatory enzymes like iNOS and COX-2, and suppressing key factors in inflammation signaling pathways such as NF-B, FOXO3a, and SIRT1(Parvez et al., 2019)

The authors proposed that chronic acetaminophen use may have generated glutathione deficiency and that this was in some way responsible for overproduction of 5-oxoproline

Despite these promising results, this study has certain limitations owing to the lack of a more in-depth exploration of the healing mechanisms

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119 , e39e75 (2016)
