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[85], this is because there is a deficiency of amylolytic LAB that produces D-lactic acid, and there are also challenges associated with the gene modification of D-lactic acid-producing LAB, such as Lactobacillus delbrueckii

To this end, the treatment variable (placebo/NAC), the potential moderator, and their interaction will be included in the model

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In cases where the drugs are repurposed from previously approved rare or non-rare indications and where robust information on the safety and mechanism of action exist, dose selection for the new indication can be informed by the previously approved doses for other indications

Testing is useful only in helping to exclude other disorders that might present with features similar to MdDS

[DOI] [PubMed] [Google Scholar] 38.Crowther L.M., Mathis D., Poms M., Plecko B