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Description
Treatment with SFN activates the NRF2 signaling pathway, mitigating oxidative stress injury and attenuating the inflammatory response associated with psoriasis

doi: 10.3389/fnut.2022.1050099 87

TETs TET proteins constitute a category of enzymes that play a crucial role in oxidizing 5mC to 5-hydroxymethylcytosine (5hmC) and subsequent oxidation products, thereby indirectly facilitating DNA demethylation

They have a role in inflammatory bowel disease, gastrointestinal cancer, metabolic disorders, and cardiovascular diseases (86)

NNMT had previously been identified as upregulated in obese adipose tissue, several solid tumours, and ageing tissue more broadly, where its activity correlates with depleted SAM and elevated 1-methylnicotinamide (MNA)

doi: 10.1007/s11010-008-9742-4
