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2024;10(1):e23507

Despite the existence of several therapeutic modalities, namely psychotherapy and antidepressants, there are several problems associated with the therapy of this disease, such as the development of resistance and relapses after the end of therapy

Besides T cell activation, DCs are also crucial for the augmentation of cytotoxic T lymphocytes (CTLs) population in the TME

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Despite numerous pre-clinical studies reporting positive pharmacodynamics of turmeric extracts and curcumin, the main issues in translating the pharmacological effects to clinical efficacy have been to overcome its poor pharmacokinetics and to deliver significant amounts of the biologically relevant forms of the actives to various tissues