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Daumke, O., Roux, A

Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritis

The intranasal route ensures rapid central nervous system penetration while avoiding peripheral side effects

The body protection compound designation reflects its originally studied role in gastrointestinal tissue protection, though its repair effects extend far beyond the gut

doi: 10.1210/clinem/dgab153 11

1 MP most often occurs in 30 to 40 year old individuals with a reported incidence rate of 4.3 cases per 10,000 patient years in the general population and 247 cases per 100,000 patient years in individuals with diabetes mellitus