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Cell (2012) 149(6):126983.10.1016/j.cell.2012.04.026 8 ValenteLJGrayDHMichalakEMPinon-HofbauerJEgleAScottCLet alp53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa

maximum injection time 200 ms, the resolution was 50,000 at 200 Th)

Therefore, endogenous anti-oxidative systems play an important role in cell survival under physiological and pathological conditions

Mitochondrial fusion is necessary to repair cell damage, form networks, and exchange genetic information [311]

however, excessive production or insufficient clearance leads to oxidative and nitrosative stress, which can damage lipids, proteins, and nucleic acids

Innovative foci in disease investigation have emerged, encompassing obesity, type 2 diabetes, and hepatic steatosis, all intimately linked to developmental exposures to EDCs