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Peak plasma levels are typically achieved 24 hours after oral administration [5][12]

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Thus, understanding the mechanisms of internalisation and whether this process involves heterodimeric receptors (Wang et al ., 2023) would be intriguing [234]

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Among the main inflammatory mediators, CRP plays a crucial role in atherogenesis by promoting complement activation, enhancing macrophage lipid uptake, stimulating pro-inflammatory cytokine release, inducing monocyte tissue factor expression, impairing endothelial function, and inhibiting nitric oxide production, further aggravating vascular injury (Shrivastava et al

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