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Arch Physiol Biochem (2008) 114(3):18394

Cardiolipin is a key phospholipid of the electron transport chain (ETC) complexes, but it is prone to oxidation and disruption of the mitochondrial membrane structure under pathological conditions

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Possible causes include: Low serotonin levels Hormonal imbalances (which may account for the disproportionate number of women who suffer from migraines) What are Conventional Medical Treatments for Migraine Headaches