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The reduction in PPAR expression could be linked to the absence of its physiological ligand or the suppression of the peroxisome proliferator response element (PPRE) [129, 130]
The reason for these aforementioned side effects may be correlated with the physiological function of HGF/c-Met in many organs, including cytoprotective, regenerative, and reduction of apoptosis after injury ( Inhibitors of c-Met Downstream Mediators To solve the side effects mentioned above, several therapy strategies have been suggested
[DOI] [PMC free article] [PubMed] [Google Scholar] 78.OShea TM, Allred EN, Dammann O, et al
The 0.3 mg dose produced 6.0% reduction
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Tendons and ligaments have less robust blood supply than muscle, which can make recovery more prolonged
