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Tesofensine is a CNS-active triple monoamine reuptake inhibitor that suppresses appetite by prolonging serotonin, norepinephrine, and dopamine signaling in hypothalamic satiety centres

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One 2017 study published in Scientific Reports showed that just 11 days of 5-Amino-1MQ led to measurable improvements in obesity-related biomarkers in mice fed a high-fat diet

This excellent safety profile doesn't eliminate the need for medical oversight