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The magnitude of these changes, 8.6mm Hg for SBP and 3.1 mm Hg for DBP, represents a clinically relevant reduction in a patient population which is considered difficult to treat

If these symptoms worsen and, patient develops life-threatening reactions such as anaphylaxis, Stevens-Johnson syndrome and epidermal necrosis, emergency treatment is required

Merck KGaA

DosSantos MF, Devalle S, Aran V, Capra D, Roque NR, Coelho-Aguiar JM, et al
Cell Death Discovery (2020) 6(1):20
If mitochondria are attacked and damaged by oxidative molecules they slow down and start to make less ATP