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Additionally, the inhibition of Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway demonstrated that cytokine-induced inflammation is also targeted by melatonin [181]

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Production of this hormone is stimulated by irradiation of skin by the suns ultraviolet rays

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Das Nebenwirkungsprofil ist grundstzlich als moderat einzustufen, wobei die meisten unerwnschten Ereignisse mild bis moderat ausgeprgt sind

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Most patients report that the initial injection-site reactions fade within 25 days

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