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doi: 10.21037/atm-21-4162

Nascas animal studies suggest that acetyl-L-carnitine, a crucial mediator of fat metabolism and energy production throughout the body, plays a special role in the brain, where it works at least in part by preventing the excessive firing of excitatory nerve cells in brain regions called the hippocampus and frontal cortex

To provide a more thorough theoretical foundation for treating disorders associated to TMAO, larger-scale clinical trials are needed to validate TMAOs potential as a biomarker for various diseases along the gut-organ axis

acetyl L-carnitine hydrochloride, vegetable capsule (coating agent: hydroxypropyl methylcellulose), anti-caking agents: silicon dioxide, magnesium salts of fatty acids.

M., White O., Sutton G