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In studies involving individuals with obesity or type 2 diabetes, Tirzepatide use resulted in significant reductions in body weight compared to placebo or other standard diabetes medications

When ferroptosis occurs, there is an increase in levels of a small range of divalent irons, which is referred to as unstable iron pool phenomenon (LIP) ( 3+ transferrin (TF) binds and is transported to tissues

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

conceived and designed the research

CISD2 promotes resistance to sorafenib-induced ferroptosis by regulating autophagy in hepatocellular carcinoma