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[DOI] [PMC free article] [PubMed] [Google Scholar] Liu Y., Wang M., Luo G., Qian X., Wu C., Zhang Y., Chen B., Leung E.L., Tang Y

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Nrf2 is considered to be a key part of organismal antioxidants since several of Nrf2s downstream genesincluding the previously described system Xc and GPX4 are involved in reversing ferroptosis ( 3.2 Ferroptosis in HSCs Hematopoietic stem cells (HSCs) are the source of human blood cells because they have the capacity to self-renew, self-repair, and rebuild hematopoietic function

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It works by neutralizing free radicals and altering the production of melanin, the pigment responsible for skin color