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Otherwise, if increased angiogenesis appears as dysregulation, as a likely possibility, regardless of beneficial effects, there is a considerable probability that increased angiogenesis precedes the complications and impedes uncontrolled VEGF, the egr-1 gene, carcinoma, and the NO-system [1]

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Biochemistry 39 , 11691179 (2000)

The most common side effects reported by patients include: Nausea Dizziness Hot flashes Blood pressure fluctuations Liver and kidney complications To reduce the risk of an adverse side effect, make sure you advise your doctor about all medical conditions you might be experiencing and any drugs you are taking to treat them