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For example, rat striatal homogenates incubated with Cu 2+ and other heavy metal cations exhibit significant reactivity toward thiols, resulting in a reduction in specific binding sites on D2 dopamine receptors (Scheuhammer and Cherian, 1985[374])

doi: 10.1007/s12602-022-09992-8 141 SmithE

, Hale, T

Transcription activator factor 3 (ATF3) could activate the unfolded protein response (UPR) and promote the formation of ADM in pancreatitis in the presence of KRAS G12D ( KRAS G12D could activate enhancer networks in progenitor cells associated with pancreatitis to drive PDAC development ( KRAS G12D -induced ALK4 ligand activator A upregulation in transformed glandular follicle cells (Zhao et al., 2020)

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Bandgar, Prajakta S