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Skin purging is a phenomenon that some people with breakout-prone skin can experience after using a leave-on exfoliant or a particular new ingredient for the first time.

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We found that 1,2-DCP was conjugated with glutathione in the liver, and that the glutathione-conjugated forms of 1,2-DCP, including a potential carcinogen that contains a chloride atom, were excreted into bile by the bile canalicular membrane transporter, ABCC2

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