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Current treatments are laden with menopausal-like side effects and many cause cessation or chemical alteration of the reproductive cycle, neither of which is conducive to achieving a pregnancy

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Also, individuals with COMT defects can be at higher risk for accumulating too much peroxynitrites which builds up in their bodies, causing stiffness and muscle pain or brain fog and cardiovascular problems

Lipid storage myopathies are considered inborn errors of metabolism affecting the fatty acid metabolism and leading to accumulation of lipid droplets in the cytoplasm of muscle fibers