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The cancelled Phase I trial that would have tested oral BPC-157 in 42 healthy volunteers never published results, leaving that data inaccessible

doi: 10.1016/j.annonc.2021.05.355

Therefore, therapeutic target to restore the TJ barrier integrity may provide effective therapeutic and preventive approaches against IBD

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In this context, citrate is transported out of the mitochondria into the cytosol via the mitochondrial citrate carrier SLC25a1 and - with the help of ATP citrate lyase functions as an acetyl donor to support the generation of acetyl CoA and fatty acid-derived derivatives

Bibliography Khavinson VKh et al