intracellular conc of glutathione in hela cells Frontiers Frontiers | Glutathione: A Samsonian

Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome

doi: 10.1016/j.biopsych.2006.06.011

TRPC1 can regulate vascular endothelial cell proliferation, migration, and NO production by sensing extracellular stimuli and regulating Ca 2+ signals [170]

PMID: 27674433

Initial tests include: FBC and film Serum ferritin Serum folate Reticulocyte count if anaemia or macrocytosis Intrinsic factor antibodies (lab will reflexly test if low B12 levels)

The largest contributors to the list of potential drug targets in this study were proteins (9 out of 25) involved in the LPS biosynthesis pathway (Sarkar et al