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By eliminating acetyl groups from the lysine residues of proteins, HDACs not only inhibit gene transcription, but also cause alternative post-translational lysine modifications including methylation, ubiquitination, and sumoylation [36]

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doi: 10.1093/humupd/dmw016 63 LiMYangMZhouXFangXHuWZhuWet al

doi: 10.1089/ars.2010.3393

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Comparing past and present serum urate measurements can demonstrate progress
