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Neurotransmitter Synthesis: Neurotransmitters, chemicals vital for brain function and mental health, rely on PLP for their synthesis

Cyanocobalamin injection is commonly used for vitamin B12 deficiency related to pernicious anemia, dietary deficiency, gastrointestinal conditions, or surgeries that reduce absorption

By looking at the gene expression patterns, Li's team first found that the pathway that produces vitamin B12 was significantly altered in the skin bacteria of people with acne, compared with the skin bacteria of people without acne

a number of management protocols exist

To unpack why the mechanism matters for dosing: NNMT sits at a metabolic crossroads

Hydroxycobalamin (nitric oxide scavenger) An excellent form to start supplementation with, well-tolerated, those patients that cannot tolerate methyl well do better on this form