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Here are some common causes: Dietary deficiency, mainly in vegans and vegetarians Pernicious anemia, an autoimmune issue with intrinsic factor production Gastric disorders, like atrophic gastritis or gastrectomy Malabsorption conditions, including Crohns disease and celiac disease Certain medications, like proton pump inhibitors and metformin Signs and Symptoms Requiring Medical Intervention Its important to know the signs of vitamin B12 deficiency

Vitamin B12 is key for making red blood cells and keeping the nervous system working right

Nor do fiveor even fiftyloading doses provide long-lasting protection for people with other B12 absorption issues

Oral supplements work as a slow climb

doi: 10.1007/s11596-018-1862-9