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AOD9604 is another fragment (177-191) of the human growth hormone that binds to GH receptors and produces a GH-like effect on the metabolism of cartilage without stimulating the proliferation of cells

Published by: Sources/Disclosures Source: Garvey WT, et al

de Lange EC, Danhof M, de Boer AG, Breimer DD

Nitric oxide ultimately leads to the formation of RNS (reactive nitrogen species) which is known to cause mitochondrial damage and is therefore suggested to be a critical agent in chondrocyte function and apoptosis

Even greater effects of might be expected in individuals exposed to higher levels of oxidants such as tobacco smokers