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Further alterations in intracellular redox balance driven by lower GSH availability induce cell death and enhance T2 signature protein expression We previously demonstrated that 15LO1-PEBP1 complex activation consistently upregulates the expression of T2-signature gene/protein expression, including MUC5AC, periostin (POSTN), and CCL26 (6, 10, 14)

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174,175 Acute liver injury induced by carbon tetrachloride leads to activation of the Wnt/-catenin signalling pathway, which manifests as an increase in the level of the Wnt target gene AXIN2

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