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[DOI] [PubMed] [Google Scholar] 63.Shimizu S., Kitada M., Ishikawa H., Itokazu Y., Wakao S., Dezawa M

Similarly, astrocyte-specific inhibition of NF-B by overexpressing IB the dominant-negative inhibitor of NF-B under the glial fibrillary acidic protein (GFAP)-promoter, prevents myelin loss and reduces TNF, IL-1, and CCL2 [181]

Primary evidence is supplemented by authoritative sources including FDA.gov, NIH.gov, MayoClinic.org, and ClevelandClinic.org due to limited recent peer-reviewed publications on this specific query

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It inhibits gastrointestinal motility and delays gastric emptying after meals, thereby reducing appetite