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N hot ng bng cch c ch hot ng ca tyrosinase, gim sn xut melanin v chuyn i melanin c sn xut thnh sc t nh hn, do t c hiu qu lm trng da, mang li ln da u mu v m hn, ng thi lm sng s i mu v vt mn

Compounds such as curcumin 21 , resveratrol 22 , and quercetin 23 were reported to possess neuroprotective, anti-inflammatory, and antioxidant activities that could address the pathological manifestations of PD 24

It is likely that as the condition worsens, so the probability of identifiable biomarkers for the disease increases, making it crucial to study severely ill patients

Statistical significance was assessed using analysis of variance (ANOVA) followed by Tukeys multiple comparison tests

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The very large biliary-to-blood concentration ratio (AUC bile /AUC blood = 30 9.4) demonstrates that the active hepatobiliary route is the primary route of elimination