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Binding specificity of the mouse cerebral cortex receptor for small cholecystokinin peptides

It was designed at Monash University in Australia to isolate growth hormone's fat-metabolizing activity while stripping out everything else the growth-promoting effects, the IGF-1 elevation, the insulin antagonism, the fluid retention

The subjects lost an average of 11% of their body weight over four weeks of treatment

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Its key for those with severe deficiencies or long-term symptoms

They are more stable and resistant to exopeptidases and endopeptidases due to the lack of terminal amine and carboxylic acid groups and a limited access to the cleavage sites [113]