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[PubMed] [Google Scholar] 108.Hagiwara M., Endo T., Hidaka H

We then further characterized one peptide, ES2, showing that it disrupts FOXO4-TP53 foci, activates TP53 mediated apoptosis and preferentially binds FOXO4 compared to TP53

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The compound suppresses lipogenesis in a concentration-dependent manner, with doses of 30-60 M reducing lipid accumulation by 50-70% in cultured adipocytes

Men, meanwhile, are typically heavier, have a larger body surface area and they tend to have more water in their bodies