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The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

TGF-, transforming growth factor-

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In fact, they can take years to become noticeable

When searching for potential biomarkers of disease status, it was determined that individuals with konzo did have a higher incidence of albumin carbamoylation, a post-translational modification likely induced by increased exposure to a toxic byproduct of linamarin degradation, cyanate 29