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J Neuroimmunol 246:6977 Saeed U, Compagnone J, Aviv RI, Strafella AP, Black SE, Lang AE, Masellis M (2017) Imaging biomarkers in Parkinsons disease and Parkinsonian syndromes: current and emerging concepts

In the Phase Ib dose escalation study (NCT02205398), 6 out of 13 c-MET positive mCRC patients whose tumors have become resistant to anti-EGFR treatment treated with capmatinib plus cetuximab achieved stable disease (disease control rate (DCR) of 46.2%) (Delord et al., 2020)

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Once usage stops, effects fade within weeks

In cell studies, folate deficiency upregulates miR-22 and miR-149