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Exercise and Mitochondrial Respiration Mitochondria are the primary source of ATP synthesis within the cell through the electron transport chain, and several factors could affect this activity, such as oxidative stress, nitric oxide, and substrate availability

On the other hand, glutamate may offer antioxidant effects via various pathways

The occurrence of NAFLD in the general population has been found to be about 2734 % in the USA, 2030 % in Europe, 2040 % in Western countries, 2030 % in the Middle East, 15 % in the Far East, 930 % in India and 18 % in Pakistan ( Reference Festi, Schiumerini and Marzi 11 )

The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD) J

Molecules 27:6429

These compounds are able to selectively accumulate in mitochondria, scavenge ROS, improve mitochondrial function, and delay the course of disease in animal models of ALS (65)
