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The induced-fit conformational change in response to DA binding likely leads to larger binding free energy changes, primarily caused by conformational changes and the formation of non-covalent interactions within the binding site yielding larger enthalpy differences, upon binding 49

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ACSS2-mediated acetyl-CoA synthesis from acetate is necessary for human cytomegalovirus infection

The only effective treatment to date involves a substance called interferon-, often in combination with an agent called ribavirin, and has a cure rate of approximately 40 percent