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10.1111/bph.14823 Br

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Whether these adaptations would be beneficial, neutral, or potentially problematic depends on factors that current research cannot address

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Gao 2023 (human GLP1R-variant series) puts a number on it at the GLP-1 receptor: cAMP output saturates at roughly 10% (103%) receptor surface expression, so full effect sits far below full occupancy

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