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Induction of leptin resistance through direct interaction of C-reactive protein with leptin

Notably, higher interleukin concentrations were associated with more severe behavioral symptoms (Ashwood et al., 2011)

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The H-bond network is only observed for OCTN2 in the occluded conformation and is absent in the inward-facing conformation, supporting that the network helps to stabilise a kinked conformation of TM11 that packs against TM2