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A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women

Cancer Res (2000) 60(16):43726

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377 Vorinostat (SAHA), an FDA-approved CTCL, induces autophagic cell death and reverses drug resistance in hepatocellular carcinoma (HCC), 378 facilitates Parkin acetylation-dependent mitophagy in cervical cancer, 379 and protects against ischemia/reperfusion injury by preserving mitochondrial homeostasis in clinical studies
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The influx of neutrophils and the activation of important genomic signal transduction pathways, including AP-1 and nuclear factor-kappa B (NF-kB), increase inflammatory activity and tissue destruction (47)