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Isothiocyanates: a class of bioactive metabolites with chemopreventive potential

In addition, with an in-depth understanding of the molecular mechanism of mitochondria, personalized targeted therapy has become the focus of future medical care
doi: 10.1080/00103624.2020.1789163 60 FoyerC
For example, in cultured endothelial cells, lipoic acid was found to inhibit IKK-, an enzyme that promotes the translocation of redox-sensitive and pro-inflammatory transcription factor, nuclear factor-kappa B (NFB) from the cytosol to the nucleus (46)
doi:10.1016/S0140-6736(18)32590-X Zhang W, Liu Y, Ge M
Because of the low toxicity of vitamin B12, no tolerable upper intake level was set by the Food and Nutrition Board in 1998 when the RDA was revised