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Molecular effects were evaluated using hippocampal immunohistochemistry and bulk RNA sequencing

In summary, we believe this in vitro system to study fibroblast-epithelial crosstalk, within the context of IPF, provides a platform which will aid in the identification and validation of novel targets.

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Acetyl-L-Carnitine (ALC) is a modified amino acid that supports cellular energy production by assisting in the transport of fat into the mitochondria where it is converted into ATP (cellular fuel).* ALC is a highly bioavailable form of carnitine that can cross the blood-brain barrier, where it helps to neutralize free radicals, supports mitochondrial function and helps to maintain normal neurotransmitter activity.* Clinical studies suggest that ALC helps to maintain optimal neurological health.*