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Further investigations are needed to determine the value of H3K27me3 as a predictive marker for establishing sensitivity to epigenetic-based therapies (EZH2 inhibitors, BRD4 targeted therapies) in tumors such as malignant peripheral nerve sheath tumor and melanoma

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Cannarella R, La Vignera S, Condorelli RA, Mongioi LM, Calogero AE

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