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Not all B12 that you eat or take in supplements is absorbed and research indicates that to achieve a sufficient daily dose of B12, you should take at least five to 50 micrograms daily or 1,000 to 2,000 micrograms weekly (Del Bo et al., 2019

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Most approved nasal formulations are liquid-based sprays that contain small-molecule drugs like sumatriptan to treat migraines and large molecules, including vitamin B12 and vasopressin [42]

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doi: 10.1016/j.freeradbiomed.2010.02.038
