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[DOI] [PubMed] [Google Scholar] [71].Kang JY, Lee JO

Cette molcule stimule galement la production de bile, qui joue un rle crucial dans l'limination des toxines par le foie

Ubiquitination is the process by which ubiquitin is added to the lysine residue of the substrate protein by enzymes E1, E2, and E3, which eventually leads to the degradation of the protein by the proteasome

2008;117(15):e312

Glutathiones strategic position between metal scavengers (GSH and PC), detoxification mechanisms (GST) and cellular reductants (AsA-GSH cycle and antioxidative enzymes) makes the GSH redox system (GSSG/GSH) perfectly integrated for signaling functions

Results Neuronal GCLC knockout leads to brain atrophy accompanied by neuronal cell death To examine how the declines in GCLC and glutathione might affect brain homeostasis, we prepared GCLC floxed X CaMKII-Cre (GCLC-KO) mice whose GCLC expression is deleted in calcium/calmodulin-dependent protein kinase II (CaMKII)-positive neurons
