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doi: 10.1038/s41577-020-00490-y 48 LiuJLXuXRixiatiYWangCYNiHLChenWSet al

In cortical neurons subjected to hypoxia/reoxygenation, HGF protects from apoptosis via the ERK pathway and, at a lesser extent, the PI-3K/AKT pathway (He et al., 2008)

In short, if you experience worse tingling after B12 injections, it might result from the B12 deficiency itself, rather than the treatment or injections

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The gaps in our knowledge and future questions represent a roadmap to the next level of research that can further elucidate L-carnitines impact on cardiovascular health