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(2002) investigated peptidase activity on porcine buccal mucosa and found aminopeptidase N to be the primary enzyme degrading peptides such as Leu-enkephalin, with only 18 9% peptide remaining after 2 h at 37 C [64]

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Short-chain fatty acids (SCFA) Short-chain fatty acids (SCFAs) are products of bacterial metabolism, deriving from the fermentation of indigestible fibers

If something changes, like say an increase of swelling or pressure, the nerve can easily become compressed

PMID 31428651 Bhave S, et al