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miRNAs also control mitochondrial dynamics and redox balance, both essential for metastatic potential and treatment adaptation [119]

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So from zero, no testosterone, which is chemically castrated, you're miserable, you have no sexual function, you're at increased risk of all these other chronic diseases that can kill you

[DOI] [PMC free article] [PubMed] [Google Scholar] 145.Nakamura S, Kugiyama K, Sugiyama S, Miyamoto S, Koide S, Fukushima H, Honda O, Yoshimura M, Ogawa H